Epitalon

Also known as: Epithalon, Epithalone, Pineal tetrapeptide

Evidence Tier C-Dhigh riskadvancednot approved

Pineal tetrapeptide discussed in aging literature for melatonin/circadian and telomerase pathways. Evidence gaps significant.

Not Approved

This substance is not approved by any major regulatory body for human therapeutic use. All information is derived from preclinical research, limited clinical studies, or off-label contexts.

Evidence Gaps

Significant evidence gaps exist for this substance. Available literature is heterogeneous, independently unreplicated, or relies heavily on secondary synthesis. Claims should be treated as exploratory hypotheses.

Overview

Epitalon is a tetrapeptide frequently described as influencing melatonin/circadian biology and telomerase-related pathways, but evidence quality is heterogeneous and independent replication is limited. Secondary synthesis suggests intranasal 10-30 mg/day for 20-30 days and intramuscular 5-10 mg/day for 10-20 days, with periodic courses. Sparse modern safety datasets; high uncertainty.

Research Details

Mechanism of Action

Proposed influence on melatonin/circadian biology and telomerase-related pathways; evidence quality heterogeneous.

Study Dose Range

Secondary synthesis: intranasal 10-30 mg/day (20-30 days); IM 5-10 mg/day (10-20 days).

Administration Routes

subcutaneous, intramuscular, intranasal

Onset / Timeline

Often marketed as weeks-long courses; treat as hypothesis.

Expected Effects

Longevity/circadian claims; telomerase association not established as fact.

Adverse Effects

Sparse modern safety datasets; high uncertainty.

Contraindications

No established data.

Interaction Notes

Unknown.

Related Goals

Longevity & Anti-AgingSleep & Relaxation

Available From

Amino Club

consumer RUO · COA: product page COA viewer

10 mg / 20 mg (variant-dependent) · variant-dependent on product page

Consumer RUO; review product details carefully

Vendor page uses the spelling 'Epithalon'. The listing is mapped back to the canonical epitalon peptide record.

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QC: third-party purity testing; product-level COA on page

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Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.