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BPC-157

Also known as: Body Protection Compound 157, PL 14736, stable gastric pentadecapeptide

Evidence Tier Cmed-high riskintermediatenot approved

Preclinical cytoprotective peptide studied for tissue repair and GI protection in animal models.

FDA Safety Flag

The FDA has identified this substance as one that may present significant safety risks when used in compounding, including concerns about immunogenicity, impurity characterization, and/or insufficient safety information.

WADA S0

This substance is explicitly listed under WADA S0 (Non-Approved Substances). If you are subject to anti-doping rules, use of this substance is prohibited at all times.

Not Approved

This substance is not approved by any major regulatory body for human therapeutic use. All information is derived from preclinical research, limited clinical studies, or off-label contexts.

Overview

BPC-157 is a 15-amino-acid peptide derived from a protein found in human gastric juice. Preclinical literature describes cytoprotective, angiogenic, and NO-system modulation signals, but the mechanism is not settled and is largely inferred from animal models. FDA has warned that compounded drugs containing BPC-157 may pose risks including immunogenicity concerns and insufficient safety information for proposed routes. WADA explicitly lists BPC-157 under S0 non-approved substances.

Research Details

Mechanism of Action

Preclinical cytoprotective and angiogenic signaling via NO-system modulation; mechanism not settled, largely inferred from animal models.

Study Dose Range

Rodent: ~10 µg/kg systemic; oral exposure at µg/kg levels. No established human dosing.

Administration Routes

subcutaneous, oral

Onset / Timeline

Animal models: endpoints assessed over days to weeks (2-4 weeks in injury models).

Expected Effects

Preclinical: angiogenesis markers, tissue repair signals, GI mucosal protection in rodent models.

Adverse Effects

Insufficient human data; immunogenicity risk flagged by FDA; impurity characterization concerns.

Contraindications

No established human contraindications (insufficient data).

Interaction Notes

No robust human interaction map; avoid confident stacking claims.

Related Goals
Tissue Repair & Recovery
Known Interactions

caution with TB-500

Commonly marketed as a stack/blend in consumer market; clinical interaction evidence limited; treat as uncertain.

caution with Thymosin Beta-4

Commonly co-marketed; limited interaction evidence; treat as uncertain.

Available From

Amino Club

consumer RUO · COA: product page COA viewer

10 mg / 20 mg (variant-dependent) · from ~$49.99 to ~$84.99 (variant-dependent)

Consumer RUO; review product details carefully

Consumer-facing vendor with on-page COA presentation. Product-level affiliate routing is available for this peptide.

USVisit Vendor

QC: third-party purity testing; product-level COA on page

Shipping: US/ROW (verify current policy) · affiliate: public program

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RUO vs Human Use

How to think about research-use-only products, approved drugs, and why RUO language does not make a listing trustworthy by itself.

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How to Reconstitute Peptides

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Frequently Compared

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Actin-sequestering peptide with clinical data in ophthalmic wound healing and preclinical tissue repair.

Tier B-C

TB-500

Marketed thymosin beta-4 fragment (LKKTETQ actin-binding motif) studied for soft-tissue repair in preclinical models.

Tier C

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Copper peptide complex with substantial topical/cosmetic literature for skin and hair repair.

Tier B-C

Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.