MGF E-domain

Also known as: Mechano Growth Factor, IGF-1Ec splice variant

Evidence Tier Cextreme riskadvancednot approved

IGF-1 splice variant peptide studied preclinically for muscle repair signaling.

WADA S2

This substance falls under WADA S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics). If you are subject to anti-doping rules, this category of substances is prohibited at all times.

No Human Data

No human exposure data has been identified for this substance. All available evidence comes from animal models or in vitro studies. Safety in humans is completely unknown.

Overview

MGF (Mechano Growth Factor) E-domain relates to IGF-1 splice variants and muscle repair signaling. Preclinical localized delivery studies exist. The mechanism involves IGF-1 receptor signaling with differences across variants. WADA lists MGF under growth factor modulators.

Research Details

Mechanism of Action

IGF-1 splice variant involved in muscle repair signaling; IGF-1 receptor signaling with variant-specific differences.

Study Dose Range

Preclinical: localized delivery studies. No established human dosing.

Administration Routes

subcutaneous

Onset / Timeline

Preclinical outcomes vary by model.

Expected Effects

Muscle repair signaling in preclinical models.

Adverse Effects

Limited data; growth-factor class concerns apply.

Contraindications

No human data.

Interaction Notes

Unknown.

Related Goals

Muscle Growth & StrengthTissue Repair & Recovery

Available From

No vendors currently listed for this peptide.

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Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.