Humanin

Also known as: HN, HNG, Humanin analogue

Evidence Tier Cmed-high riskadvancednot approved

Mitochondrial-derived micropeptide with preclinical cytoprotective and neuroprotective research.

Not Approved

This substance is not approved by any major regulatory body for human therapeutic use. All information is derived from preclinical research, limited clinical studies, or off-label contexts.

No Human Data

No human exposure data has been identified for this substance. All available evidence comes from animal models or in vitro studies. Safety in humans is completely unknown.

Overview

Humanin (and its potent analogue HNG) is a mitochondrial-derived micropeptide. Cytoprotective and neuroprotective actions are described in reviews with proposed roles in mitochondrial stress and metabolic regulation. Stroke/neuroprotection models exist preclinically. Unknown safety in humans.

Research Details

Mechanism of Action

Cytoprotective and neuroprotective actions; proposed roles in mitochondrial stress and metabolic regulation.

Study Dose Range

Preclinical and limited translational; stroke/neuroprotection models.

Administration Routes

subcutaneous

Onset / Timeline

Model-dependent in preclinical studies.

Expected Effects

Preclinical: cytoprotection, neuroprotection. No proven human benefit.

Adverse Effects

Unknown in humans.

Contraindications

No data.

Interaction Notes

Unknown.

Related Goals

Longevity & Anti-AgingCognitive & Neuroprotection

Available From

No vendors currently listed for this peptide.

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Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.